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Reaction id: 0401011009_09, verified by Personal Chemistry ©
(S)-1-(3-bromoph...
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1,2,4-triazole
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K2CO3
CuI
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NMP
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2i
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Yield: 96% Time: 3600s Temperature: 195 °C
Chemicals
| Name |
MW [g/mol] |
Density [g/ml] |
Amount [mmol] |
Mass/Volume |
| Substrate 1 |
200.084 |
1.000 |
0.500 |
100.042 mg |
| 288-88-0 |
69.067 |
1.000 |
1.000 |
69.067 mg |
| CuI |
190.444 |
1.000 |
0.050 |
9.522 mg |
| K2CO3 |
138.204 |
1.000 |
1.000 |
138.204 mg |
| NMP |
99.133 |
1.028 |
6.948 |
670.000 µl |
| Product 1 |
188.234 |
1.000 |
0.000 |
0.000 mg |
Keywords
Aromatic, Catalysis, Catalytic, Catalyzed, Substitution, Ullmann Coupling
Comments
Work-up: The reaction mixture was filtered and the solvent evaporated under reduced pressure. The product was isolated by silica gel flash chromatography.
Characterisation: The product was characterised by 1H and 13C NMR.
Instrument Settings
Absorption level: Normal
Pre-stirring time: 0s
References
Wu, Y.-J.; He, H.; Heureux, A. L. Tet. Lett. 2003, 44, 4217-4218
Analysis
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