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Reaction id: 0211121025_25, verified by Personal Chemistry ©
1014
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464
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100
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TEA
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EtOH
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P 25
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Yield: 70% Time: 720s Temperature: 160 °C
Chemicals
| Name |
MW [g/mol] |
Density [g/ml] |
Amount [mmol] |
Mass/Volume |
| 17452276 |
136.176 |
1.220 |
1.100 |
122.782 µl |
| 107971 |
89.094 |
1.000 |
1.000 |
89.094 mg |
| 100107 |
149.193 |
1.000 |
1.100 |
164.112 mg |
| TEA |
101.193 |
0.726 |
1.500 |
209.076 µl |
| EtOH |
46.069 |
1.000 |
60.778 |
2800.000 µl |
| Product 1 |
338.433 |
1.000 |
1.000 |
338.433 mg |
Keywords
Condensation, Cyclisation, Heterocyclic
Comments
Synthesis: The product was formed as a solid. We only used 1.5 eq of base in the reaction. Perhaps more base could drive the reaction further towards product.
Work-up: The solid was filtered off and washed with EtOH. It was then recrystalised from EtOH:DCM..
Instrument Settings
Absorption level: High
Pre-stirring time: 0s
References
Khodair, A. I; Nielsen, J. Heterocycles 2002, 57, 6, 1017-1022
Analysis
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0211121025_25A.pdf