|
|  |
Reaction id: 0210161014_16, verified by Personal Chemistry ©
163
|
|
1544
|
|
|
 |
EtOH
|
|
P16
|
Yield: 66% Time: 300s Temperature: 170 °C
Chemicals
| Name |
MW [g/mol] |
Density [g/ml] |
Amount [mmol] |
Mass/Volume |
| 95545 |
108.144 |
1.000 |
1.000 |
108.144 mg |
| 600226 |
102.089 |
1.130 |
1.000 |
90.344 µl |
| EtOH |
46.069 |
1.000 |
43.413 |
2000.000 µl |
| Product 1 |
160.176 |
1.000 |
1.000 |
160.176 mg |
Keywords
Addition, Condensation, Heterocyclic, Ring formation
Comments
Synthesis: This product was unexpectedly formed when using oxalacetic acid, because of decarboxylation. See entry 0210161014_12. When this ortho-diamine reacted with bromopyruvic acid it did not give the desired product.
Work-up: The product formed as a solid which was filtered off and washed with EtOH.
Instrument Settings
Absorption level: Normal
Pre-stirring time: 0s
References
Moffitt, M.; Schultz, H. P. J. Org. Chem. 1977, 42, 14, 2504-2505
Katoh, A.; Yoshida, T.; Ohkanda, J. Heterocycles. 2000, 52, 2, 911-920
Dujardin, G.; Leconte, S.; Bénard, A.; Brown, E. Synlett. 2000, 1, 147-149
Analysis
|
|
|
|
|
0210161014_16A.pdf