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Reaction id: 0210101010_01, verified by Personal Chemistry ©
1138
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1544
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EtOH
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P 1
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Yield: 58% Time: 300s Temperature: 170 °C
Chemicals
| Name |
MW [g/mol] |
Density [g/ml] |
Amount [mmol] |
Mass/Volume |
| 2835974 |
123.155 |
1.000 |
1.000 |
123.155 mg |
| 600226 |
102.089 |
1.130 |
1.000 |
90.344 µl |
| EtOH |
46.069 |
1.000 |
43.413 |
2000.000 µl |
| Product 1 |
175.187 |
1.000 |
1.000 |
175.187 µl |
Keywords
Addition, Condensation, Heterocyclic, Ring formation
Comments
Work-up: A solid formed in the reaction. It was filtered off and washed with EtOH. The LCMS was run on the solid after the filtraton. For comparison, see entry 0210091021_01, which in this case gave a lower yield as the carboxylic acid was used instead of the methyl ester.
Instrument Settings
Absorption level: Normal
Pre-stirring time: 0s
References
Moffitt, M.; Schultz, H. P. J. Org. Chem. 1977, 42, 14, 2504-2505
Katoh, A.; Yoshida, T.; Ohkanda, J. Heterocycles. 2000, 52, 2, 911-920
Dujardin, G.; Leconte, S.; Bénard, A.; Brown, E. Synlett. 2000, 1, 147-149
Analysis
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0210101010_01A.pdf