|
|  |
Reaction id: 0211131016_07, verified by Personal Chemistry ©
1212
|
|
1123
|
K2CO3
|
 |
2-Propanol
|
|
Product 7
|
Yield: 31% Time: 300s Temperature: 180 °C
Chemicals
| Name |
MW [g/mol] |
Density [g/ml] |
Amount [mmol] |
Mass/Volume |
| 637898 |
126.177 |
1.000 |
0.556 |
70.091 µl |
| 286204 |
98.145 |
0.970 |
0.500 |
50.590 µl |
| K2CO3 |
138.204 |
1.000 |
0.500 |
69.102 mg |
| 2-Propanol |
60.096 |
1.000 |
38.442 |
2310.220 µl |
| Product 1 |
224.322 |
1.000 |
0.000 |
0.000 µl |
Keywords
Addition, Ring opening, SN2, Substitution
Comments
Synthesis: This kind of reaction does not work, or works not so well, if the epoxide is sterically hindered.
Purification: The solution was filtered through a 5µ PTFE filter and the product purified by preparative RPLC.
Instrument Settings
Absorption level: Normal
Pre-stirring time: 0s
References
Carey, F. A.; Sundberg R. J. Advanced Organic Chemistry Part B: Reactions and Synthesis, p 636; 3rd ed.; Plenum Press: New York, 1990
Analysis
|
|
|
|
|
0211131016_07G.pdf